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Clinikill Platinum-500mL Free Sample

Clinikill Platinum

HOSPITAL GRADE DISINFECTANT CONCENTRATE NON-TOXIC, pH NEUTRAL

Pharmachem’s Clinikill Platinum Kills COVID-19

australian made & owned

TGA APproved to 2021 standard

Do you want to safeguard your practice from COVID-19?

Clinikill Platinum™ is TGA approved to kill COVID-19 in 5 MINUTES

Clinikill Platinum™ Disinfectant Concentrate is environmentally friendly, non-corrosive, non-toxic and safe to use around people and animals.

Easy to use, you simply dilute with water and apply as a wash or spray.

Suitable to use on all hard surfaces such as:
• Waiting room furniture and floors    • Examination tables and tubs    • Reception desk    • Trolleys and cages    • Kitchen and bathroom area

Why TRUST Clinikill Platinum™?

To prevent resistance, it is critically important to test disinfectants regularly against today’s standards.

What may have been efficacious 20, 10 or even 5 years ago, may not be today.

Clinikill Platinum™ has conducted all trials in 2020 and 2021 and commits to conducting ongoing trials into the future.

Made and Owned in Australia, Clinikill Platinum is your partner in safeguarding your practice, patients and staff.

ACTIVE INGREDIENTS

Benzalkonium Chloride 54g/L (equivalent to 5.4% w/v)
Polyhexamethylene Biguanide 4g/L (equivalent to 0.4% w/v)

Available in:
1L, 5L & 20L packs

Additional Technical Links

Accordion Content

Clinikill Platinum™ combines two proven and highly effective Biocides (Biocides are a group of substances used for the control of organisms that are harmful to human and animal health).

1. Poly (hexamethylene biguanide) Hydrochloride (PHMB) which has a variety of antimicrobial applications. It is used as a disinfecting agent to control, prevent or destroy hramful microorganisms (i.e. bacteria, viruses or fungi). It is environmentally friendly and is non-corrosive and non-toxic to both humans and animals.

There has been no reported instances of bacteria acquiring resistance to PHMB.

Source: British Journal of Environmental Sciences
“Polyhexamethylene Biguanide Hydrochloride: Features and Applications”

2. Benzalkonium Chlorides (BZK) have widespread applications due to broad spectrum antimicrobial properties effective against bacteria, fungi, yeasts and viruses.
For this reason, they are used worldwide in disinfectant/antiseptic solutions within the pharmaceutical industry, hospitals and healthcare facilities, food processing and domestic households (just to name a few).

Source: American Society for Microbiology
“Benzalkonium Chlorides: Uses, Regulatory Status and Microbial Resistance”

How were the final directions established?

As a requirement for registration by the TGA, Independent Trials were conducted by Eurofins* to prove its efficacy in 2020.

Different dilution rates with H2O were tested resulting in the final rates required to pass the rigorous standards of the TGA (note attached test results).

What do these results indicate?

Compared to the dilution rates with H2O recommended by other products, these recent trials conclude a higher concentration of disinfectant to H2O is essential to ensure efficacy.

In fact, it is strongly believed that resistance has developed by bacteria to BZK over a number of years due to indiscriminate use and low kill rate dilutions. This resistance is even considered one of the factors in promoting antibiotic resistance.

Source: American Society for Microbiology
“Widely used Benzalkonium Chloride Disinfectants can Promote Antibiotic Resistance”

Source: International Journal of Infections
“Antibiotic Resistance Induction by Benalkonium Chloride in Exposure in Nosocomial Pathogens”

Antimicrobial Resistance (AMR) and its pivotal partnership with Disinfectants.

In 2015, the Australian government published a strategy stating that, “Antimicrobial resistance (AMR) is one of the biggest threats to human and animal health today” 1. In 2019, the AVA published their own paper, “Antimicrobial Resistance Strategy – 2020 and beyond”2. One of their key objectives was to “improve infection prevention and control measures across human health and animal care settings to help prevent infection and the spread of resistance”.

AMR occurs when microorganisms such as bacteria, viruses or fungi become resistant to antimicrobial medicines. The three main classes of antimicrobials are ANTIBIOTICS, ANTISEPTICS & DISINFECTANTS.

In order to successfully implement antimicrobial stewardship, it is essential to include best practice infection prevention and control (IPC). This is why the proper use of approved disinfectants (as AMR’s) require greater understanding and acceptance as partners in the AMR battle. Thousands of suppliers around the world sell “unregulated and unproven” products based simply on the name “disinfectant”.

In 2018, the American Society for Microbiology published a paper “Widely used Benzalkonium Chloride (BAC) disinfectants can promote antibiotic resistance”3. BAC is the most commonly used member of the QAC family of disinfectants and are used in products such as surface disinfecting agents, consumer and pharmaceutical products.

The problem is not the efficacy of BAC itself as an antimicrobial, it’s the indiscriminate use or underuse of the product at varying concentrations or directions, (not dissimilar to the debate around AMR with antibiotics).

It is therefore critical when selecting an appropriate disinfectant to:

  1. Consider the products claims and directions to suit your requirements;
  2. Request independent trial data proving efficacy. If they have it, they can provide it.
  3. Ask when these trials were conducted. Have they been conducted since 2020?

Due to the increase in resistance by microbes, what may have been effective 20, 10, or even 5 years ago may not be effective today. Be informed and include “proven” and “up to date” disinfectants as a critical tool in your antimicrobial stewardship.

1 https://www.amr.gov.au/

2 https://www.ava.com.au/siteassets/resources/fighting-antimicrobial-resistance/ava-submission-national-amr-strategy-2020-and-beyond.pdf

3 https://journals.asm.org/doi/full/10.1128/AEM.01201-18

*Eurofins is a trademark of Euronfins Scientific (Ireland) Ltd.